The Venture family must travel to space to repair an orbiting space station that Dr. Venture's father built in the 1970s, but a mysterious space phantom could be haunting the station!

To protect the Venture compound while Brock is on his yearly mountain survival sabbatical, Dr. Venture builds a panic room and a robotic bodyguard, which are soon put to the test.

Dr. Venture is offered a job by theme park owner and cartoon magnate Roy Brisby, who won't take no for an answer in his quest for worldwide entertainment dominance.

Dr. Venture's new experiment has the entire family interested--not to mention trapped inside! The Ventures' strange new neighbor, master of mysticism Dr. Orpheus, may be the only one who can help them escape.

On a scientific expedition in the Bermuda Triangle, Doc's experimental equipment awakens and possibly enrages the submerged ghost of Major Tom, a test pilot who crashed in an experimental aircraft designed by Doc's father.

Dr. Venture, Pete White and Master Billy Quizboy are invited to take part in a top secret government think tank run by supergenius Professor Impossible.

The Monarch sends Dr. Girlfriend undercover to seduce Dr. Venture in order to inject him with a body-altering serum.

The Monarch finally has the Venture family right where he wants them hanging upside down above the Amazon river! But his victory is postponed when Dean suffers a strange but fairly common injury, acute testicular tortion.

Always short on cash, Dr. Venture decides to unload some of his father's old scientific equipment in a huge yard sale that attracts fellow scientists and super-villains alike.