Dr. Lewis tries to get a mentally disturbed individual admitted to the psych ward. Carter has a difficult day, treating many members of wedding party, suffering from food poisoning. Dr. Ross finally visits Carol, eight weeks after her suicide attempt. Dr. Greene deals with an elderly gentleman having a difficult time letting go of his dying wife. He also discovers that Jenn passed the bar exam.

Carol returns after her eight week absence, finding Doug holding himself responsible. Carter finds himself watching over a mysterious, mentally ill singing woman. Susan clashes with Dr. Kayson over a diagnosis. Dr. Greene treats a domestic violence victim.

Carter has a difficult day when he has to identify a dead teenager and notify his parents. It doesn't help that he notifies the wrong family. Doug woos Carol, despite Taglieri's presence in her life. Benton clashes with brother-in-law Walt after he neglects family duties.

A business contractor with a bad heart gathers his family around him in the ER as he prepares for the end. Dr. Ross helps an asthmatic teenage girl when her mother doesn't have the funds. Carter worries that he may have contracted an STD from Liz. Dr. Lewis treats a teenager with alcohol poisoning. Jenn Greene prepares to move to Milwaukee.

The air conditioning quits on the hottest day in October which, coupled with closed ERs in Chicago's other two hospitals, leads to an extremely hectic day. Dr. Ross treats a six-year-old suffering from a cocaine overdose; Ivan Gregor, the liquor store owner, shoots and seriously wounds a young teenager. Susan's immature sister Chloe drops by, wreaking havoc in Susan's life. Doug picks up a pharmaceutical saleswoman, much to Carol's displeasure.

Benton and Langworthy interview for the Starzl fellowship. A drunk Chloe throws a tantrum in the hospital. Benton saves a man with a throat wound, earning Morganstern's praise. Carter has a good day, winning a bottle of champagne and getting three leads on apartments. Carol has second thoughts about moving in with Tag after a spontaneous kiss with Doug.

Hathaway treats a rape victim. Walt brings Benton's mother to the ER with a sprained ankle. Carter shows his annoyance toward Benton and his stand-offish attitude. Mark calls in sick to spend time with his wife, leaving Doug as a hectic acting chief. Div shows signs of snapping, overreacting at the smallest provocation. The ER gets a new desk clerk, 'Bob'.

Carter and Benton treat a suicidal transgender woman. Doug feels like a 'kept man' in his relationship with Linda Farrell. A patient entrusts Carol with the particulars in an accident. Cvetic continues to battle his demons, ending up wandering down the middle of a crowded street.

A severe blizzard leaves the ER utterly devoid of patients, leaving the staff free to goof off. In the middle of their fun, a call comes from dispatch, informing the ER of a 40-car pile-up with dozens of casualties. The ER goes from being deserted to capacity. All surgeons are called in. Bob surprises everyone with a quick and life-saving decision. A new doctor, Angela Hicks, arrives just at the right time. Ross and Linda return from the Caribbean just as Carol makes a surprise announcement.