Mike's dog pays the price when Edie crashes his dinner date with Susan. Meanwhile, Gabrielle realizes that her lawnboy is taking their fling to heart - and that Carlos may actually be catching on. Also, Bree goads Rex into therapy, where the doctor may be the one who needs the most help. Lynette resorts to drastic measures to keep her kids in line, but it blows up in her face.

The women decide to go ahead with the big dinner party that the late Mary Alice Young had planned to host, despite the more-than-minor disturbances in their own lives. Adulterous Gabrielle finds herself with a nine-year-old blackmailer who catches Gabrielle in the act in her affair with gardener John. Also, Bree struggles to keep her crumbling marriage a secret. Lastly, Susan bares all--in more ways than one--as she confronts her ex.

Cash-strapped Mrs. Huber figures out that Susan had something to do with Edie's house fire and tries to blackmail her. Meanwhile, Carlos becomes suspicious that Gabrielle is seeing another man, but targets the wrong suspect---the cable guy instead of gardener John. Also, Lynette balks when the twins' teacher insists the boys have ADD but tries to salvage the matter by seprating the boys. Lastly, Bree struggles with her rebellious son Andrew after Rex moves out.

A break-in on Wisteria Lane leaves the neighbors feeling vulnerable, especially Susan, who reluctantly accepts a date with a persistent policeman after Mike appears indifferent to her. Rex takes the kids away for the weekend as a lonely Bree finds herself bonding with Zach. Meanwhile, Lynette and Tom pull out all the stops to get their uncontrollable twins Porter and Preston accepted at a prestigious private school, and the unexpected arrival of Carlos' mother puts a crimp in Gabrielle's covert love life.

Lynette locks horns with officious mom Maisy Gibbons at the twins' school who is trying to produce a "politically correct" play about "Little Red Riding Hood." Meanwhile, Susan continues to investigate the mystery of Zach's sudden disappearance. She soon finds out his father Paul put him in Seacrest, a mental institution. She and Julie then go to investigate. Mama Solis comes closer to discovering Gabrielle's dirty little secret of her affair, and Bree comes undone when Rex suggests they hire a sex surrogate.

Susan and Edie decide to follow Mike and his houseguest Kendra on their night out together. Lynette becomes steadily more dependent on the twins' ADD medication. In the meantime Gabrielle becomes jealous of the "other" woman in John's life. And Bree's kids mutiny when they learn their dad has moved out. Tom is not happy when Lynette tries to take over his concept of new "Spotless Scrubs" to his clients.

In the aftermath of tragedy with Bree's son Andrew running over Carlos' mother Juanita Solis, the residents of Wisteria Lane take stock of their lives. Meanwhile, Susan grows suspicious of Mike's real reason for moving to the street. Lynette reaches the breaking point in her addiction to the twins' ADD medication as she tries other measures like acupuncture to release her stress. The mysterious Mr. Shaw gets down to business as he develops a relationship with Edie. Lastly, Gabrielle confesses her adulterous affair to a priest while Carlos' mother Juanita is in the hospital.

Looking to give her life a purpose, Gabrielle decides to organize a glamorous Halston fashion show for charity highlighting the ladies of Wisteria Lane. Bree and Rex are at odds on how to punish Andrew for putting Mrs. Solis in the hospital and finding drugs in his room. The police investigate a toy chest that Paul Young dumped in the river. Lastly, Lynette uses her business acumen to poach a nanny, Claire, but ends up getting involved between her current employer, Alexis.

Uber mom Maisy Gibbons returns, and her secret life intersects with Bree's. Meanwhile Gabrielle's predicament worsens as she gets a taste of her own medicine, courtesy of Carlos's jailhouse confession. Susan plans to take her relationship with Mike to the next level, and Lynette, suspicious (and a little jealous) of her new nanny decides to secretly videotape her. Lastly, Susan sends Zach Young back home to his father, who makes a startling admission of his own.