ComedyDramaSci-Fi & Fantasy
Two strangers are drawn to a mysterious pharmaceutical trial that will, they're assured, with no complications or side-effects whatsoever, solve all of their problems, permanently. Things do not go as planned.
Diagnosed with schizophrenia, Owen is the black sheep of the wealthy Milgrim clan. After losing his job, he enrolls in an experimental drug trial.
When her pilfered stash of pills runs out, troubled Annie tries to quit -- but ends up blackmailing her way into the Neberdine study.
Muramoto notices irregularities in Annie and Owen's data. He questions Owen, who recalls the worst night of his life: his brother's engagement party.
After taking the B pill, Annie and Owen find themselves on 1980s Long Island entangled in a strange caper involving a lemur.
Annie and Owen are Arlie and Ollie, grifters attending a séance at the mysterious Neberdine mansion in the 1940s.
Azumi tells James the whole truth about the study's snags and urges him to call his estranged mother, an esteemed therapist.
Owen and Annie take the C pill. No longer connected, he belongs to a Mafia family, and she's a medieval guide hired by an ailing elf princess.
Annia and Ellia continue their quest, and Owen's mafioso father pressures him to protect the family. Greta counsels a bereaved Gertie.
Owen and Annie meet again as a disgraced Icelandic spy and a CIA operative who helps him. Greta implores James to shut down the trial.
After the subjects are discharged, James and Azumi face Neberdine's CEO. Owen and Annie part ways -- until a startling headline sparks a reunion.
Cast: Emma Stone, Jonah Hill, Sonoya Mizuno, Justin Theroux, Sally Field, Kathleen Choe, Danny Hoch, James Monroe Iglehart, Dai Ishiguro, Allyce Beasley, Stephen Hill, Sejal Shah, Billy Magnussen, Aaralyn Anderson, Gabriel Byrne, Jemima Kirke, Julia Garner, Nate Craig, Alexandra Curran, Trudie Styler, Christian DeMarais, Cailin Loesch, Hannah Loesch, Geoffrey Cantor, Rome Kanda, Ramya Pratt, Zach Shearon, Hank Azaria, Ariel Kavoussi, Selenis Leyva
Genres: Comedy, Drama, Sci-Fi & Fantasy
Maturity rating: TV-MA
Emma Stone
Annie Landsberg
Jonah Hill
Owen Milgrim
Sonoya Mizuno
Dr. Azumi Fujita
Justin Theroux
Dr. James K. Mantleray
Sally Field
Dr. Greta Mantleray
Kathleen Choe
3
Danny Hoch
5
James Monroe Iglehart
Carl
Dai Ishiguro
Head Control Tech
Allyce Beasley
11
Stephen Hill
7
Sejal Shah
First Medical Tech
Billy Magnussen
Jed Milgrim
Aaralyn Anderson
Belle Milgrim
Gabriel Byrne
Porter Milgrim
Jemima Kirke
Adelaide
Julia Garner
Ellie Landsberg
Nate Craig
Phil
Alexandra Curran
Holly Milgrim
Trudie Styler
Angelica Milgrim
Christian DeMarais
Mike Milgrim
Cailin Loesch
Lady of Arquesta
Hannah Loesch
Lady of Arquesta
Geoffrey Cantor
Frank
Rome Kanda
Dr. Muramoto
Ramya Pratt
Vicky / Green Hoodie Woman
Zach Shearon
Hank Azaria
Hank Landsberg (voice)
Ariel Kavoussi
Female Ad Buddy / Bianca Forsythe / Dragonfly (voice)
Selenis Leyva
Patricia Lugo
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